I've had my share of disasters, but the best one in our family wasn't mine. I won't say whose, cuz I'd be in the dog house if she found out I posted it to the world, but: this anonymous lady was making chili. Hmmm. No chili powder in the pantry. No problem, my son tells her: cayenne pepper is the same thing, different name. So she subbed it, tablespoon for tablespoon.
Man, that was some hot chili! 5 alarm, at least! Coulda used that stuff as paint remover!